Realnova Healthcare

FEATURES OF
Pantoprazole & Domperidone Tablets

• Dual-action therapy for effective management of acid-related gastrointestinal disorders

• Pantoprazole (Proton Pump Inhibitor) reduces gastric acid secretion and promotes healing of the stomach and esophageal lining

• Domperidone enhances gastrointestinal motility and helps prevent nausea, vomiting, and reflux

• Provides rapid and sustained relief from acidity, heartburn, and indigestion

• Effective in GERD, peptic ulcer disease, gastritis, and reflux esophagitis

• Helps relieve symptoms like bloating, epigastric discomfort, and post-meal fullness

• Improves gastric emptying, reducing chances of acid regurgitation

• Generally well-tolerated and suitable for short- and long-term use as prescribed

• Convenient once-daily dosing for better patient compliance

features of Pantoprazole Gastro-Resistant Tablets:

✅ 1. Proton Pump Inhibitor (PPI)

Pantoprazole belongs to the PPI class of medicines that reduce excess stomach acid by blocking the proton pump in the stomach lining.

✅ 2. Gastro-Resistant / Enteric-Coated

These tablets are specially coated to:

• Prevent breakdown in stomach acid

• Dissolve in the intestine for better absorption

• Reduce stomach irritation

✅ 3. Effective Acid Control

• Provides long-lasting acid suppression (up to 24 hours)

• Relieves heartburn and acid reflux symptoms

✅ 4. Used for Multiple GI Conditions

Commonly prescribed for:

• GERD (Gastroesophageal Reflux Disease)

• Peptic ulcers

• Zollinger-Ellison syndrome

• Gastritis

• H. pylori combination therapy

✅ 5. Once-Daily Dosage

Usually taken once daily before meals for effective control.

✅ 6. Fast Symptom Relief

Starts reducing acid production within hours of intake.

✅ 7. Suitable for Long-Term Therapy

Can be used for short-term as well as maintenance treatment under medical supervision.

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📌 Main Features & Benefits ✅ Acid Reduction

• Rabeprazole reduces stomach acid production by blocking the gastric H⁺/K⁺-ATPase enzyme (proton pump).

• This helps relieve symptoms like heartburn, sour stomach, indigestion, and acid reflux.

🩹 Useful for Healing and Prevention

It’s prescribed for conditions where lowering acid helps:

• Gastroesophageal reflux disease (GERD) – reduces acid reflux into the food pipe.

• Erosive oesophagitis – helps heal acid damage to the food pipe.

• Peptic ulcers (gastric and duodenal) – promotes healing.

• Helicobacter pylori infection (with antibiotics) – aids bacterial eradication by lowering acid.

• Zollinger-Ellison syndrome – controls excessive acid production.

⏱️ Fast and Long-Lasting Action

• Starts working within about 1 hour after taking it.

• Often delivers 24-hour acid suppression with once-daily dosing.

🩺 Main Uses

This combination is commonly used for:

• Gastroesophageal Reflux Disease (GERD) – heartburn, acid reflux

• Indigestion / Dyspepsia – stomach discomfort, fullness, burning

• Esophagitis – inflammation of the food pipe

• Acidity and related symptoms

• Relief from nausea and vomiting associated with acid-related disorders

✨ Because it combines acid suppression and better GI motility, it often works faster and more completely than esomeprazole alone. 

Features

• Rapid, Dual Relief: Combines antacid and antiflatulent actions for fast, comprehensive digestive comfort.Shinor Biosciences -Wonne International -

• Sugar-Free Options: Available for individuals monitoring sugar intake (e.g., diabetes).Shinor Biosciences -

• Versatile Presentation: Often flavored (like mint) and sold in convenient syrup form, making it adaptable for adults and children

FEATURES

• Digestive Enzymes Support – Fungal Diastase helps in breaking down starch, while Pepsin aids protein digestion, improving overall digestion.

• Relieves Indigestion & Bloating – Useful in conditions like dyspepsia, loss of appetite, flatulence, and heaviness after meals.

• Nutritional Supplement – Enriched with B-Complex vitamins (B1, B2, B3, B6, B12, etc.) that support metabolism and energy production.

• Improves Appetite – Helps stimulate appetite in patients with anorexia or general weakness.

• Supports Recovery – Beneficial in post-illness weakness, convalescence, and digestive disorders.

• Dual Action Formula – Combines enzyme activity with vitamin supplementation for better digestive health.

FEATURES

• Proton Pump Inhibitor (PPI) for IV administration

• Provides rapid suppression of gastric acid secretion

• Used in patients unable to take oral medication

• Effective in the treatment of GERD, peptic ulcers, and Zollinger-Ellison syndrome

• Helps in prevention and management of upper gastrointestinal bleeding

• Convenient lyophilized powder form for reconstitution

• Ensures quick onset of action with sustained acid control

 features of Magaldrate-Simethicone Oral Suspension (170 ml) — a commonly used antacid and anti-gas liquid medicine:

✅ 1. Active Ingredients

• Magaldrate – an antacid that neutralizes excess stomach acid.

• Simethicone – an anti-foaming/carminative agent that helps break down gas bubbles to relieve bloating and flatulence.

Typical composition per 5 ml (may vary slightly by brand):
• Magaldrate ~400 mg
• Simethicone ~20 mg

✅ 2. Therapeutic Action

• Neutralizes stomach acid to reduce acidity and heartburn.

• Relieves gas and bloating by making gas easier to pass.

• Helps ease dyspepsia, indigestion, sour stomach, and post-meal discomfort.

✅ 3. Common Uses / Indications

• Heartburn and acid reflux

• Excess stomach acidity

• Indigestion (dyspepsia)

• Gas, bloating, and flatulence

• Discomfort/pain due to acidity

✅ 4. Dosage Form & Presentation

• Oral suspension liquid, usually in a 170 ml bottle.

• Often available in flavored liquid to improve taste (e.g., mint, saunf).

✅ 5. How It Works (Mode of Action)

• Magaldrate neutralizes gastric acid, raising pH and reducing acid irritation.

• Simethicone lowers the surface tension of gas bubbles, helping small gas pockets merge into bigger ones that are easier to eliminate.

✅ 6. Benefits

• Provides dual-action relief for both acidity and gas symptoms.

• Offers relatively quick symptomatic relief when taken as directed.

FEATURES OF ESOMEPRAZOLE SODIUM FOR INJECTION

1. Active Ingredient:
   Contains Esomeprazole Sodium, a proton pump inhibitor (PPI) that reduces gastric acid secretion.

2. Therapeutic Use:

   • Used for the treatment of gastroesophageal reflux disease (GERD) in patients unable to take oral medication.

   • Helps in healing of erosive esophagitis.

   • Used for prevention and treatment of gastric ulcers associated with NSAID therapy.

   • Provides acid control in critically ill patients (stress ulcer prophylaxis).

3. Mode of Action:

   • Inhibits the H⁺/K⁺ ATPase enzyme system at the secretory surface of gastric parietal cells, blocking the final step in acid production.

4. Dosage Form:

   • Lyophilized powder for reconstitution and intravenous (IV) administration.

   • Usually supplied in single-dose vials (e.g., 40 mg).

5. Administration:

   • Given by slow IV injection or infusion when oral therapy is not feasible.

   • Reconstituted with compatible solvents before use.

6. Advantages:

   • Provides rapid and effective acid suppression.

   • Ensures controlled gastric pH in acute care or NPO (nothing by mouth) patients.

   • Equivalent efficacy to oral esomeprazole once oral route is resumed.

7. Stability:

   • Stable under recommended storage conditions; must be used soon after reconstitution.

   • Typically stored below 25°C and protected from light.

8. Packaging:

   • Supplied in sterile glass vials, often with an ampoule of sterile diluent (depending on manufacturer).

FEATURES OF Pantoprazole for Injection

• Proton Pump Inhibitor (PPI): Effectively reduces gastric acid secretion by inhibiting the H⁺/K⁺-ATPase pump in stomach lining.

• Rapid Onset of Action: Provides quick relief from acid-related symptoms when oral administration is not possible.

• Used in Critical Care Settings: Suitable for patients who are NPO (not taking medicines orally), post-operative, or in ICU.

• Indicated For:

  • GERD with erosive esophagitis

  • Zollinger–Ellison syndrome

  • Severe gastric and duodenal ulcers

  • Stress-related mucosal damage

• IV Formulation: Available as a lyophilized powder for reconstitution before IV administration.

• Flexible Administration: Can be given as IV bolus (slow push) or IV infusion as per clinical need.

• Maintains Stable Gastric pH: Helps prevent bleeding in high-risk patients.

• Well-Tolerated Profile: Generally safe with minimal side effects.

• Consistency in Acid Suppression: Provides reliable and prolonged acid-control compared to some other PPIs.

• Convenient Once-Daily Dosing: Most patients require just 40 mg once daily, depending on clinical indication.

FEATURES
Omeprazole Capsules:

• Used to treat acid-related disorders such as:

  • Gastroesophageal Reflux Disease (GERD) – long-term reflux of stomach acid into the esophagus.

  • Peptic ulcers – ulcers in the stomach or duodenum.

  • Zollinger–Ellison syndrome – excessive acid production due to tumors.

  • Erosive esophagitis – inflammation and damage of the esophagus caused by stomach acid.

• Helps in the prevention and treatment of ulcers caused by NSAIDs (painkillers).

• Used in combination therapy for Helicobacter pylori (H. pylori) eradication, which causes stomach ulcers.

• Provides symptomatic relief of heartburn, acidity, indigestion, and sour stomach.